About Us

We’re on a mission to make cancer more detectable.

Early detection saves lives

Imagion Biosystems exists to help detect cancer earlier and with greater precision, so patients have the best chance at effective treatment.

Our Mission

At Imagion Biosystems, we are working to change how cancer is found and treated.

Too often, cancer is detected late, after it has already spread, or patients undergo unnecessary procedures due to uncertainty in imaging results.

Our mission is to provide imaging tools that bring clarity where today’s methods fall short. We focus on enabling clinicians to detect cancer earlier, with greater confidence, so patients have more options and better outcomes.

Our Technology

We are advancing MagSense® molecular MRI (mMRI), a new approach that combines the power of MRI with molecular-level targeting.

MagSense® uses bio-safe magnetic nanoparticles (superparamagnetic iron-oxide nanoparticles, SPIONS) linked to molecules that attach to specific cancer biomarkers.

By combining the high resolution of MRI with the specificity of our imaging agents, we have the potential to detect tumors, with certainty, that are up to 10 times smaller than what current standard imaging can detect, helping clinicians see cancer sooner and more precisely, without exposing patients to radiation.

aNANOtation
WHAT ARE SPIONS?

Superparamagnetic iron oxide nanoparticles (SPIONs) are tiny, biocompatible particles that exert a local magnetic force in response to the pulsed magnetic field of the MRI, making them ideal for non-invasive detection with standard diagnostic imaging. They can be used for diagnostics, therapy, and tracking of cells within the body, offering a versatile and promising tool in biomedicine.

Our Journey

Founded with a vision to revolutionize cancer detection, Imagion Biosystems has grown from early-stage innovation to active clinical development.

Key milestones include:

    • Completion of a multi-site Phase I clinical study of our MagSense® HER2 imaging agent in breast cancer
    • IND preparation for Phase II clinical trials to evaluate diagnostic performance in detecting nodal metastases in HER2-positive breast cancer
    • Development of additional MagSense® imaging agents for prostate and ovarian cancer detection
    • Ongoing partnerships with leading institutions and clinical sites

MagSense® HER2 Imaging Agent Clinical Study

Imagion Biosystems is preparing for a Phase II clinical trial of our MagSense® HER2 imaging agent, focused on breast cancer detection.

Our trials are designed to demonstrate the potential of molecular MRI to improve diagnostic confidence, guide biopsies, and reduce unnecessary procedures.

Meet our team of Imagioneers

Geoff Hollis
CFO & Company Secretary
Marie Zhang, PhD
VP Research & Preclinical Development
Elana Levin
Director of Quality Assurance
Carmen Solkowski
Director of Operations
Mee Wa Wong, PhD
Director of Product Market Development
Sormeh Mahjouri
Program Director
Koushik Govindarajan
Clinical Scientist
Nitika Neha
Clinical Trial Manager
Eric Smith-Nguyen
Sr. Research Associate
Hannah Campbell
Senior Accountant
Casie Ost
Marketing Communications Manager
Michael Shun
Nanoparticle Production Tech
Kevin Forero
Nanoparticle Production Tech

Recent Milestones

December 2023

Imagion was selected to present in a Poster Spotlight Discussion at San Antonio Breast Cancer Symposium; MagSense® HER2 Imaging Agent: Molecular MRI for the Detection of Axillary Nodal Metastasis in Subjects with HER2+ Breast Cancer.  More >

December 2023

October 2023

Imagion announces progress with MagSense® Folate Receptor program in multiple translatable animal models of Ovarian Cancer at AACR’s Special Conference on Ovarian Cancer.  More >

October 2023

August 2023

Imagion signs MOU with Prestige Biopharma to develop early pancreatic cancer diagnostic test.  More >

August 2023

July 2023

Closed enrollment for Phase 1 of the MagSense® HER2 Imaging Agent (MSH2IA) study.

July 2023

June 2023

Expands collaboration with Siemens Healthineers Pty Ltd. of Australia and agree to collaborate in the US in anticipation of undertaking the Phase 2 study for MagSense® HER2 imaging agent.  More >

June 2023

March 2023

The Phase 1 data and independent expert review support IBX continued development of the MagSense® nanoparticle technology for molecular MRI of cancer. More >

March 2023

Feb 2023

Updated strategy to develop the MagSense® nanoparticle technology for use with clinical MRI systems.

Feb 2023

Feb 2023

Independent review by radiologists confirmed the MagSense® HER2 Imaging Agent produces a unique and differentiable image contrast in lymph nodes suspicious for tumor. This unique molecular signature is critical to discriminate lymph nodes with tumor cells from normal nodes and has the potential to improve nodal assessment for staging over current methods.

Feb 2023

Dec 2022

Presented interim data from MagSense® HER2 Breast Cancer Phase I study at the San Antonio Breast Cancer Symposium showing imaging agent showed no safety findings of significance and reaches its target tissue (axillary lymph nodes) with the planned route of administration and shows unique and differentiable MR contrast pattern in nodes suspicious for tumor.

Dec 2022

Sept 2022

Presented prostate cancer research data at the World Molecular Imaging Congress with MagSense® imaging agent showing high specificity and selectivity

Sept 2022

Apr 2022

Sponsored Research Agreement executed with researchers at Massachusetts General Hospital focuses on MRI 

Apr 2022

Mar 2022

MagSense® HER2 Breast Cancer Phase I study interim results indicate imaging agent is well-tolerated and is reaching patient’s lymph nodes

Mar 2022

Aug 2021

Joint Development Agreement with Global Cancer Technologies to develop nanocrystals for treatment of breast cancer

Aug 2021

May 2021

Collaboration with Patrys (ASX:PAB) for Brain Cancer imaging

May 2021

May 2021

First patient dosed in Phase I study

May 2021

Mar 2021

Receive CSIRO grant to support Prostate Cancer imaging research

Mar 2021

Mar 2020

MagSense® HER2 Breast Cancer Phase I study opens for enrolment

Mar 2020

Oct 2020

HREC approval for MagSense® HER2 Breast Cancer Phase I study in Australia

Oct 2020

May 2020

Research collaboration with Siemens

May 2020

Jul 2019

Received FDA designation as a ”Breakthrough Device”

Jul 2019

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