About Us
Early detection saves lives
Imagion Biosystems exists to help detect cancer earlier and with greater precision, so patients have the best chance at effective treatment.

Our Mission
At Imagion Biosystems, we are working to change how cancer is found and treated.
Too often, cancer is detected late, after it has already spread, or patients undergo unnecessary procedures due to uncertainty in imaging results.
Our mission is to provide imaging tools that bring clarity where today’s methods fall short. We focus on enabling clinicians to detect cancer earlier, with greater confidence, so patients have more options and better outcomes.
Our Technology
We are advancing MagSense® molecular MRI (mMRI), a new approach that combines the power of MRI with molecular-level targeting.
MagSense® uses bio-safe magnetic nanoparticles (superparamagnetic iron-oxide nanoparticles, SPIONS) linked to molecules that attach to specific cancer biomarkers.
By combining the high resolution of MRI with the specificity of our imaging agents, we have the potential to detect tumors, with certainty, that are up to 10 times smaller than what current standard imaging can detect, helping clinicians see cancer sooner and more precisely, without exposing patients to radiation.
aNANOtation
WHAT ARE SPIONS?

Our Journey
Founded with a vision to revolutionize cancer detection, Imagion Biosystems has grown from early-stage innovation to active clinical development.
Key milestones include:
- Completion of a multi-site Phase I clinical study of our MagSense® HER2 imaging agent in breast cancer
- IND preparation for Phase II clinical trials to evaluate diagnostic performance in detecting nodal metastases in HER2-positive breast cancer
- Development of additional MagSense® imaging agents for prostate and ovarian cancer detection
- Ongoing partnerships with leading institutions and clinical sites
MagSense® HER2 Imaging Agent Clinical Study
Imagion Biosystems is preparing for a Phase II clinical trial of our MagSense® HER2 imaging agent, focused on breast cancer detection.
Our trials are designed to demonstrate the potential of molecular MRI to improve diagnostic confidence, guide biopsies, and reduce unnecessary procedures.
Meet our team of Imagioneers

Geoff Hollis

Marie Zhang, PhD

Elana Levin

Carmen Solkowski

Mee Wa Wong, PhD

Sormeh Mahjouri

Koushik Govindarajan

Nitika Neha

Eric Smith-Nguyen

Hannah Campbell

Casie Ost

Michael Shun

Kevin Forero
Recent Milestones
December 2023
Imagion was selected to present in a Poster Spotlight Discussion at San Antonio Breast Cancer Symposium; MagSense® HER2 Imaging Agent: Molecular MRI for the Detection of Axillary Nodal Metastasis in Subjects with HER2+ Breast Cancer. More >
October 2023
Imagion announces progress with MagSense® Folate Receptor program in multiple translatable animal models of Ovarian Cancer at AACR’s Special Conference on Ovarian Cancer. More >
August 2023
Imagion signs MOU with Prestige Biopharma to develop early pancreatic cancer diagnostic test. More >
July 2023
Closed enrollment for Phase 1 of the MagSense® HER2 Imaging Agent (MSH2IA) study.
June 2023
Expands collaboration with Siemens Healthineers Pty Ltd. of Australia and agree to collaborate in the US in anticipation of undertaking the Phase 2 study for MagSense® HER2 imaging agent. More >
March 2023
The Phase 1 data and independent expert review support IBX continued development of the MagSense® nanoparticle technology for molecular MRI of cancer. More >
Feb 2023
Updated strategy to develop the MagSense® nanoparticle technology for use with clinical MRI systems.
Feb 2023
Independent review by radiologists confirmed the MagSense® HER2 Imaging Agent produces a unique and differentiable image contrast in lymph nodes suspicious for tumor. This unique molecular signature is critical to discriminate lymph nodes with tumor cells from normal nodes and has the potential to improve nodal assessment for staging over current methods.
Dec 2022
Presented interim data from MagSense® HER2 Breast Cancer Phase I study at the San Antonio Breast Cancer Symposium showing imaging agent showed no safety findings of significance and reaches its target tissue (axillary lymph nodes) with the planned route of administration and shows unique and differentiable MR contrast pattern in nodes suspicious for tumor.
Sept 2022
Presented prostate cancer research data at the World Molecular Imaging Congress with MagSense® imaging agent showing high specificity and selectivity
Apr 2022
Sponsored Research Agreement executed with researchers at Massachusetts General Hospital focuses on MRI
Mar 2022
MagSense® HER2 Breast Cancer Phase I study interim results indicate imaging agent is well-tolerated and is reaching patient’s lymph nodes
Aug 2021
Joint Development Agreement with Global Cancer Technologies to develop nanocrystals for treatment of breast cancer
May 2021
Collaboration with Patrys (ASX:PAB) for Brain Cancer imaging
May 2021
First patient dosed in Phase I study
Mar 2021
Receive CSIRO grant to support Prostate Cancer imaging research
Mar 2020
MagSense® HER2 Breast Cancer Phase I study opens for enrolment
Oct 2020
HREC approval for MagSense® HER2 Breast Cancer Phase I study in Australia
May 2020
Research collaboration with Siemens
Jul 2019
Received FDA designation as a ”Breakthrough Device”


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